SLC25A13-MAGI2 Fusion FISH Probe
The SLC25A13-MAGI2 Fusion FISH Probe is used to confirm a fusion of the SLC25A13 and MAGI2 genes. The fusion of the SLC25A13 and MAGI2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SLC25A13-MAGI2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-RERE | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-REOR | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-REGO | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-REGR | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-REAQ | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-ORRE | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-OROR | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-ORGO | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-GORE | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-GOOR | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-GOGO | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-GOGR | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-GRRE | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-GROR | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-GRGO | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-GRGR | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-AQRE | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-AQOR | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-AQGO | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-AQGR | 20 (40 μL) | 200 μL |
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| SLC25A13-MAGI2-20-AQAQ | 20 (40 μL) | 200 μL |
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MAGI2 Gene Summary
The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. [provided by RefSeq, Jul 2008]
Gene Name: Membrane Associated Guanylate Kinase, WW And PDZ Domain Containing 2
Chromosome: CHR7: 77646373 -79082890
Locus: 7q21.11
SLC25A13 Gene Summary
This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Gene Name: Solute Carrier Family 25 Member 13
Chromosome: CHR7: 95749531 -95951459
Locus: 7q21.3
Gene Diseases
The SLC25A13 MAGI2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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