SLC24A3-PLCB4 Fusion FISH Probe
The SLC24A3-PLCB4 Fusion FISH Probe is used to confirm a fusion of the SLC24A3 and PLCB4 genes. The fusion of the SLC24A3 and PLCB4 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SLC24A3-PLCB4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-RERE | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-REOR | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-REGO | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-REGR | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-REAQ | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-ORRE | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-OROR | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-ORGO | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-ORAQ | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-GORE | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-GOOR | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-GOGO | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-GOGR | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-GOAQ | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-GRRE | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-GROR | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-GRGO | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-GRGR | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-GRAQ | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-AQRE | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-AQOR | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-AQGO | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-AQGR | 20 (40 μL) | 200 μL |
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| SLC24A3-PLCB4-20-AQAQ | 20 (40 μL) | 200 μL |
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PLCB4 Gene Summary
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals in the retina. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2010]
Gene Name: Phospholipase C Beta 4
Chromosome: CHR20: 9049700 -9461462
Locus: 20p12.3-p12.2
SLC24A3 Gene Summary
Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Potassium-dependent sodium/calcium exchangers such as SLC24A3 are believed to transport 1 intracellular calcium and 1 potassium ion in exchange for 4 extracellular sodium ions (Kraev et al., 2001 [PubMed 11294880]).[supplied by OMIM, Mar 2008]
Gene Name: Solute Carrier Family 24 Member 3
Chromosome: CHR20: 19193289 -19703541
Locus: 20p11.23
Gene Diseases
The SLC24A3 PLCB4 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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