SLC23A2-TMX4 Fusion FISH Probe
The SLC23A2-TMX4 Fusion FISH Probe is used to confirm a fusion of the SLC23A2 and TMX4 genes. The fusion of the SLC23A2 and TMX4 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SLC23A2-TMX4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-RERE | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-REOR | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-REGO | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-REGR | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-REAQ | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-ORRE | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-OROR | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-ORGO | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-ORAQ | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-GORE | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-GOOR | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-GOGO | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-GOGR | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-GOAQ | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-GRRE | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-GROR | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-GRGO | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-GRGR | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-GRAQ | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-AQRE | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-AQOR | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-AQGO | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-AQGR | 20 (40 μL) | 200 μL |
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| SLC23A2-TMX4-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC23A2 Gene Summary
The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two required transporters and the encoded protein accounts for tissue-specific uptake of vitamin C. Previously, this gene had an official symbol of SLC23A1. [provided by RefSeq, Jul 2008]
Gene Name: Solute Carrier Family 23 Member 2
Chromosome: CHR20: 4833001 -4990939
Locus: 20p13
TMX4 Gene Summary
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and C-terminal ASP/GLU-rich calcium binding domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The encoded protein has been shown to have reductase activity in vitro. [provided by RefSeq, Jan 2017]
Gene Name: Thioredoxin Related Transmembrane Protein 4
Chromosome: CHR20: 7961715 -8000393
Locus: 20p12.3
Gene Diseases
The SLC23A2 TMX4 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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