SLC22A25-PACS1 Fusion FISH Probe
The SLC22A25-PACS1 Fusion FISH Probe is used to confirm a fusion of the SLC22A25 and PACS1 genes. The fusion of the SLC22A25 and PACS1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SLC22A25-PACS1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-RERE | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-REOR | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-REGO | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-REGR | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-REAQ | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-ORRE | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-OROR | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-ORGO | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-GORE | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-GOOR | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-GOGO | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-GOGR | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-GRRE | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-GROR | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-GRGO | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-GRGR | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-AQRE | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-AQOR | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-AQGO | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-AQGR | 20 (40 μL) | 200 μL |
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| SLC22A25-PACS1-20-AQAQ | 20 (40 μL) | 200 μL |
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PACS1 Gene Summary
This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. [provided by RefSeq, Jul 2008]
Gene Name: Phosphofurin Acidic Cluster Sorting Protein 1
Chromosome: CHR11: 65837823 -66012213
Locus: 11q13.1-q13.2
SLC22A25 Gene Summary
The Solute Carrier Family 22 Member 25 (SLC22A25) gene is located on chr11 :62931295-62997124 at 11q12.3.
Gene Name: Solute Carrier Family 22 Member 25
Chromosome: CHR11: 62931295 -62997124
Locus: 11q12.3
Gene Diseases
The SLC22A25 PACS1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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