SLC1A1-SMARCA2 Fusion FISH Probe
The SLC1A1-SMARCA2 Fusion FISH Probe is used to confirm a fusion of the SLC1A1 and SMARCA2 genes. The fusion of the SLC1A1 and SMARCA2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SLC1A1-SMARCA2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-RERE | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-REOR | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-REGO | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-REGR | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-REAQ | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-ORRE | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-OROR | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-ORGO | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-GORE | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-GOOR | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-GOGO | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-GOGR | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-GRRE | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-GROR | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-GRGO | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-GRGR | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-AQRE | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-AQOR | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-AQGO | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-AQGR | 20 (40 μL) | 200 μL |
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| SLC1A1-SMARCA2-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC1A1 Gene Summary
This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect. [provided by RefSeq, Mar 2010]
Gene Name: Solute Carrier Family 1 Member 1
Chromosome: CHR9: 4490426 -4587469
Locus: 9p24.2
SMARCA2 Gene Summary
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. [provided by RefSeq, Jan 2014]
Gene Name: SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 2
Chromosome: CHR9: 2015341 -2193623
Locus: 9p24.3
Gene Diseases
The SLC1A1 SMARCA2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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