SLC12A2-MEGF10 Fusion FISH Probe
The SLC12A2-MEGF10 Fusion FISH Probe is used to confirm a fusion of the SLC12A2 and MEGF10 genes. The fusion of the SLC12A2 and MEGF10 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SLC12A2-MEGF10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-RERE | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-REOR | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-REGO | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-REGR | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-REAQ | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-ORRE | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-OROR | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-ORGO | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-ORAQ | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-GORE | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-GOOR | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-GOGO | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-GOGR | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-GOAQ | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-GRRE | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-GROR | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-GRGO | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-GRGR | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-GRAQ | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-AQRE | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-AQOR | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-AQGO | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-AQGR | 20 (40 μL) | 200 μL |
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| SLC12A2-MEGF10-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC12A2 Gene Summary
The protein encoded by this gene mediates sodium and chloride transport and reabsorption. The encoded protein is a membrane protein and is important in maintaining proper ionic balance and cell volume. This protein is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Name: Solute Carrier Family 12 Member 2
Chromosome: CHR5: 127419482 -127525380
Locus: 5q23.3
MEGF10 Gene Summary
This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. Expression of this gene may be associated with schizophrenia, and mutations in this gene are a cause of early-onset myopathy, areflexia, respiratory distress, and dysphagia (EMARDD) as well as congenital myopathy with minicores. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Apr 2012]
Gene Name: Multiple EGF Like Domains 10
Chromosome: CHR5: 126626455 -126796910
Locus: 5q23.2
Gene Diseases
The SLC12A2 MEGF10 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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