SKAP1-ABCC11 Fusion FISH Probe
The SKAP1-ABCC11 Fusion FISH Probe is used to confirm a fusion of the SKAP1 and ABCC11 genes. The fusion of the SKAP1 and ABCC11 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SKAP1-ABCC11-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-RERE | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-REOR | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-REGO | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-REGR | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-REAQ | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-ORRE | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-OROR | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-ORGO | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-ORAQ | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-GORE | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-GOOR | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-GOGO | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-GOGR | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-GOAQ | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-GRRE | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-GROR | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-GRGO | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-GRGR | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-GRAQ | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-AQRE | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-AQOR | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-AQGO | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-AQGR | 20 (40 μL) | 200 μL |
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| SKAP1-ABCC11-20-AQAQ | 20 (40 μL) | 200 μL |
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SKAP1 Gene Summary
This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. [provided by RefSeq, Jul 2008]
Gene Name: Src Kinase Associated Phosphoprotein 1
Chromosome: CHR17: 46210801 -46507594
Locus: 17q21.32
ABCC11 Gene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: ATP Binding Cassette Subfamily C Member 11
Chromosome: CHR16: 48200821 -48269088
Locus: 16q12.1
Gene Diseases
The SKAP1 ABCC11 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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