SIRT7-CCDC57 Fusion FISH Probe
The SIRT7-CCDC57 Fusion FISH Probe is used to confirm a fusion of the SIRT7 and CCDC57 genes. The fusion of the SIRT7 and CCDC57 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SIRT7-CCDC57-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-RERE | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-REOR | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-REGO | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-REGR | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-REAQ | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-ORRE | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-OROR | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-ORGO | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-ORAQ | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-GORE | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-GOOR | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-GOGO | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-GOGR | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-GOAQ | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-GRRE | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-GROR | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-GRGO | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-GRGR | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-GRAQ | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-AQRE | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-AQOR | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-AQGO | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-AQGR | 20 (40 μL) | 200 μL |
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| SIRT7-CCDC57-20-AQAQ | 20 (40 μL) | 200 μL |
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SIRT7 Gene Summary
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008]
Gene Name: Sirtuin 7
Chromosome: CHR17: 79869814 -79876058
Locus: 17q25.3
CCDC57 Gene Summary
The Coiled-coil Domain Containing 57 (CCDC57) gene is located on chr17 :80059345-80170689 at 17q25.3.
Gene Name: Coiled-coil Domain Containing 57
Chromosome: CHR17: 80059345 -80170689
Locus: 17q25.3
Gene Diseases
The SIRT7 CCDC57 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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