SIN3A-OCA2 Fusion FISH Probe
The SIN3A-OCA2 Fusion FISH Probe is used to confirm a fusion of the SIN3A and OCA2 genes. The fusion of the SIN3A and OCA2 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SIN3A-OCA2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-RERE | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-REOR | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-REGO | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-REGR | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-REAQ | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-ORRE | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-OROR | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-ORGO | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-GORE | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-GOOR | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-GOGO | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-GOGR | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-GRRE | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-GROR | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-GRGO | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-GRGR | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-AQRE | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-AQOR | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-AQGO | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-AQGR | 20 (40 μL) | 200 μL |
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| SIN3A-OCA2-20-AQAQ | 20 (40 μL) | 200 μL |
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OCA2 Gene Summary
This gene encodes the human homolog of the mouse p (pink-eyed dilution) gene. The encoded protein is believed to be an integral membrane protein involved in small molecule transport, specifically tyrosine, which is a precursor to melanin synthesis. It is involved in mammalian pigmentation, where it may control skin color variation and act as a determinant of brown or blue eye color. Mutations in this gene result in type 2 oculocutaneous albinism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Name: OCA2 Melanosomal Transmembrane Protein
Chromosome: CHR15: 28000022 -28344458
Locus: 15q12-q13.1
SIN3A Gene Summary
The protein encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions and may mediate repression by the Mad-Max complex. [provided by RefSeq, Jul 2008]
Gene Name: SIN3 Transcription Regulator Family Member A
Chromosome: CHR15: 75661719 -75748124
Locus: 15q24.2
Gene Diseases
The SIN3A OCA2 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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