SIN3A-NEO1 Fusion FISH Probe
The SIN3A-NEO1 Fusion FISH Probe is used to confirm a fusion of the SIN3A and NEO1 genes. The fusion of the SIN3A and NEO1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SIN3A-NEO1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-RERE | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-REOR | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-REGO | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-REGR | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-REAQ | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-ORRE | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-OROR | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-ORGO | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-GORE | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-GOOR | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-GOGO | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-GOGR | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-GRRE | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-GROR | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-GRGO | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-GRGR | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-AQRE | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-AQOR | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-AQGO | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-AQGR | 20 (40 μL) | 200 μL |
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| SIN3A-NEO1-20-AQAQ | 20 (40 μL) | 200 μL |
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NEO1 Gene Summary
This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be involved in cell growth and differentiation and in cell-cell adhesion. Defects in this gene are associated with cell proliferation in certain cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Gene Name: Neogenin 1
Chromosome: CHR15: 73344824 -73597547
Locus: 15q24.1
SIN3A Gene Summary
The protein encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions and may mediate repression by the Mad-Max complex. [provided by RefSeq, Jul 2008]
Gene Name: SIN3 Transcription Regulator Family Member A
Chromosome: CHR15: 75661719 -75748124
Locus: 15q24.2
Gene Diseases
The SIN3A NEO1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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