SIAH1-FAM65A Fusion FISH Probe
The SIAH1-FAM65A Fusion FISH Probe is used to confirm a fusion of the SIAH1 and FAM65A genes. The fusion of the SIAH1 and FAM65A genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SIAH1-FAM65A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-RERE | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-REOR | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-REGO | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-REGR | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-REAQ | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-ORRE | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-OROR | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-ORGO | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-ORAQ | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-GORE | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-GOOR | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-GOGO | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-GOGR | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-GOAQ | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-GRRE | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-GROR | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-GRGO | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-GRGR | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-GRAQ | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-AQRE | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-AQOR | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-AQGO | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-AQGR | 20 (40 μL) | 200 μL |
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| SIAH1-FAM65A-20-AQAQ | 20 (40 μL) | 200 μL |
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SIAH1 Gene Summary
This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008]
Gene Name: Siah E3 Ubiquitin Protein Ligase 1
Chromosome: CHR16: 48394453 -48419229
Locus: 16q12.1
Gene Diseases
The SIAH1 FAM65A Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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