SIAE-HYLS1 Fusion FISH Probe
The SIAE-HYLS1 Fusion FISH Probe is used to confirm a fusion of the SIAE and HYLS1 genes. The fusion of the SIAE and HYLS1 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SIAE-HYLS1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-RERE | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-REOR | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-REGO | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-REGR | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-REAQ | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-ORRE | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-OROR | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-ORGO | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-GORE | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-GOOR | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-GOGO | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-GOGR | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-GRRE | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-GROR | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-GRGO | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-GRGR | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-AQRE | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-AQOR | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-AQGO | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-AQGR | 20 (40 μL) | 200 μL |
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| SIAE-HYLS1-20-AQAQ | 20 (40 μL) | 200 μL |
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SIAE Gene Summary
This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene are associated with susceptibility to autoimmune disease 6. Multiple transcript variants encoding different isoforms, found either in the cytosol or in the lysosome, have been found for this gene.[provided by RefSeq, Feb 2011]
Gene Name: Sialic Acid Acetylesterase
Chromosome: CHR11: 124505684 -124546199
Locus: 11q24.2
HYLS1 Gene Summary
This gene encodes a protein localized to the cytoplasm. Mutations in this gene are associated with hydrolethalus syndrome. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2008]
Gene Name: HYLS1, Centriolar And Ciliogenesis Associated
Chromosome: CHR11: 125753508 -125770541
Locus: 11q24.2
Gene Diseases
The SIAE HYLS1 Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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