SIAE-GRIK4 Fusion FISH Probe
The SIAE-GRIK4 Fusion FISH Probe is used to confirm a fusion of the SIAE and GRIK4 genes. The fusion of the SIAE and GRIK4 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SIAE-GRIK4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-RERE | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-REOR | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-REGO | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-REGR | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-REAQ | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-ORRE | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-OROR | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-ORGO | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-ORAQ | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-GORE | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-GOOR | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-GOGO | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-GOGR | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-GOAQ | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-GRRE | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-GROR | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-GRGO | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-GRGR | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-GRAQ | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-AQRE | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-AQOR | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-AQGO | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-AQGR | 20 (40 μL) | 200 μL |
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| SIAE-GRIK4-20-AQAQ | 20 (40 μL) | 200 μL |
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GRIK4 Gene Summary
This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
Gene Name: Glutamate Ionotropic Receptor Kainate Type Subunit 4
Chromosome: CHR11: 120531027 -120856969
Locus: 11q23.3
SIAE Gene Summary
This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene are associated with susceptibility to autoimmune disease 6. Multiple transcript variants encoding different isoforms, found either in the cytosol or in the lysosome, have been found for this gene.[provided by RefSeq, Feb 2011]
Gene Name: Sialic Acid Acetylesterase
Chromosome: CHR11: 124505684 -124546199
Locus: 11q24.2
Gene Diseases
The SIAE GRIK4 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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