SHROOM2-BHLHE41 Fusion FISH Probe
The SHROOM2-BHLHE41 Fusion FISH Probe is used to confirm a fusion of the SHROOM2 and BHLHE41 genes. The fusion of the SHROOM2 and BHLHE41 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SHROOM2-BHLHE41-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-RERE | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-REOR | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-REGO | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-REGR | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-REAQ | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-ORRE | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-OROR | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-ORGO | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-ORAQ | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-GORE | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-GOOR | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-GOGO | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-GOGR | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-GOAQ | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-GRRE | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-GROR | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-GRGO | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-GRGR | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-GRAQ | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-AQRE | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-AQOR | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-AQGO | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-AQGR | 20 (40 μL) | 200 μL |
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| SHROOM2-BHLHE41-20-AQAQ | 20 (40 μL) | 200 μL |
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SHROOM2 Gene Summary
This gene represents the human homolog of Xenopus laevis apical protein (APX) gene, which is implicated in amiloride-sensitive sodium channel activity. It is expressed in endothelial cells and facilitates the formation of a contractile network within endothelial cells. Depletion of this gene results in an increase in endothelial sprouting, migration, and angiogenesis. This gene is highly expressed in the retina, and is a strong candidate for ocular albinism type 1 syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
Gene Name: Shroom Family Member 2
Chromosome: CHRX: 9754495 -9917481
Locus: Xp22.2
BHLHE41 Gene Summary
This gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with ARNTL or compete for E-box binding sites in the promoter of PER1 and repress CLOCK/ARNTL's transactivation of PER1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation. Defects in this gene are associated with the short sleep phenotype. [provided by RefSeq, Feb 2014]
Gene Name: Basic Helix-loop-helix Family Member E41
Chromosome: CHR12: 26272958 -26278003
Locus: 12p12.1
Gene Diseases
The SHROOM2 BHLHE41 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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