SHQ1-PSMB7 Fusion FISH Probe
The SHQ1-PSMB7 Fusion FISH Probe is used to confirm a fusion of the SHQ1 and PSMB7 genes. The fusion of the SHQ1 and PSMB7 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SHQ1-PSMB7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-RERE | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-REOR | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-REGO | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-REGR | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-REAQ | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-ORRE | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-OROR | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-ORGO | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-ORAQ | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-GORE | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-GOOR | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-GOGO | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-GOGR | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-GOAQ | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-GRRE | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-GROR | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-GRGO | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-GRGR | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-GRAQ | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-AQRE | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-AQOR | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-AQGO | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-AQGR | 20 (40 μL) | 200 μL |
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| SHQ1-PSMB7-20-AQAQ | 20 (40 μL) | 200 μL |
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PSMB7 Gene Summary
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit. A pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Jul 2012]
Gene Name: Proteasome Subunit Beta 7
Chromosome: CHR9: 127115743 -127177721
Locus: 9q33.3
SHQ1 Gene Summary
SHQ1 assists in the assembly of H/ACA-box ribonucleoproteins that function in the processing of ribosomal RNAs, modification of spliceosomal small nuclear RNAs, and stabilization of telomerase (see MIM 602322) (Grozdanov et al., 2009 [PubMed 19383767]).[supplied by OMIM, Dec 2010]
Gene Name: SHQ1, H/ACA Ribonucleoprotein Assembly Factor
Chromosome: CHR3: 72798427 -72897598
Locus: 3p13
Gene Diseases
The SHQ1 PSMB7 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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