SHPRH-PKIB Fusion FISH Probe
The SHPRH-PKIB Fusion FISH Probe is used to confirm a fusion of the SHPRH and PKIB genes. The fusion of the SHPRH and PKIB genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SHPRH-PKIB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-RERE | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-REOR | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-REGO | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-REGR | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-REAQ | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-ORRE | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-OROR | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-ORGO | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-ORAQ | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-GORE | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-GOOR | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-GOGO | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-GOGR | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-GOAQ | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-GRRE | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-GROR | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-GRGO | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-GRGR | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-GRAQ | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-AQRE | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-AQOR | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-AQGO | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-AQGR | 20 (40 μL) | 200 μL |
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| SHPRH-PKIB-20-AQAQ | 20 (40 μL) | 200 μL |
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PKIB Gene Summary
This gene encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Gene Name: CAMP-dependent Protein Kinase Inhibitor Beta
Chromosome: CHR6: 122793061 -123047518
Locus: 6q22.31
SHPRH Gene Summary
SHPRH is a ubiquitously expressed protein that contains motifs characteristics of several DNA repair proteins, transcription factors, and helicases. SHPRH is a functional homolog of S. cerevisiae RAD5 (Unk et al., 2006 [PubMed 17108083]).[supplied by OMIM, Mar 2008]
Gene Name: SNF2 Histone Linker PHD RING Helicase
Chromosome: CHR6: 146205944 -146285233
Locus: 6q24.3
Gene Diseases
The SHPRH PKIB Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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