SH3RF1-SPOCK3 Fusion FISH Probe
The SH3RF1-SPOCK3 Fusion FISH Probe is used to confirm a fusion of the SH3RF1 and SPOCK3 genes. The fusion of the SH3RF1 and SPOCK3 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SH3RF1-SPOCK3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-RERE | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-REOR | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-REGO | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-REGR | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-REAQ | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-ORRE | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-OROR | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-ORGO | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-ORAQ | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-GORE | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-GOOR | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-GOGO | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-GOGR | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-GOAQ | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-GRRE | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-GROR | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-GRGO | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-GRGR | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-GRAQ | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-AQRE | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-AQOR | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-AQGO | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-AQGR | 20 (40 μL) | 200 μL |
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| SH3RF1-SPOCK3-20-AQAQ | 20 (40 μL) | 200 μL |
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SPOCK3 Gene Summary
This gene encodes a member of a novel family of calcium-binding proteoglycan proteins that contain thyroglobulin type-1 and Kazal-like domains. The encoded protein and may play a role in adult T-cell leukemia by inhibiting the activity of membrane-type matrix metalloproteinases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Gene Name: SPARC/osteonectin, Cwcv And Kazal Like Domains Proteoglycan 3
Chromosome: CHR4: 167654535 -168155741
Locus: 4q32.3
SH3RF1 Gene Summary
This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module. [provided by RefSeq, Jul 2008]
Gene Name: SH3 Domain Containing Ring Finger 1
Chromosome: CHR4: 170015406 -170192249
Locus: 4q32.3-q33
Gene Diseases
The SH3RF1 SPOCK3 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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