SH3GL1-MUM1 Fusion FISH Probe
The SH3GL1-MUM1 Fusion FISH Probe is used to confirm a fusion of the SH3GL1 and MUM1 genes. The fusion of the SH3GL1 and MUM1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SH3GL1-MUM1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-RERE | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-REOR | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-REGO | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-REGR | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-REAQ | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-ORRE | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-OROR | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-ORGO | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-GORE | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-GOOR | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-GOGO | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-GOGR | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-GRRE | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-GROR | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-GRGO | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-GRGR | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-AQRE | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-AQOR | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-AQGO | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-AQGR | 20 (40 μL) | 200 μL |
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| SH3GL1-MUM1-20-AQAQ | 20 (40 μL) | 200 μL |
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SH3GL1 Gene Summary
This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Gene Name: SH3 Domain Containing GRB2 Like 1, Endophilin A2
Chromosome: CHR19: 4360363 -4400565
Locus: 19p13.3
MUM1 Gene Summary
The Melanoma Associated Antigen (mutated) 1 (MUM1) gene is located on chr19 :1354975-1378430 at 19p13.3.
Gene Name: Melanoma Associated Antigen (mutated) 1
Chromosome: CHR19: 1354975 -1378430
Locus: 19p13.3
Gene Diseases
The SH3GL1 MUM1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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