SH3GL1-FN1 Fusion FISH Probe
The SH3GL1-FN1 Fusion FISH Probe is used to confirm a fusion of the SH3GL1 and FN1 genes. The fusion of the SH3GL1 and FN1 genes has been associated with Kidney Chromophobe. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SH3GL1-FN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-RERE | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-REOR | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-REGO | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-REGR | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-REAQ | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-ORRE | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-OROR | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-ORGO | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-GORE | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-GOOR | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-GOGO | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-GOGR | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-GRRE | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-GROR | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-GRGO | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-GRGR | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-AQRE | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-AQOR | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-AQGO | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-AQGR | 20 (40 μL) | 200 μL |
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| SH3GL1-FN1-20-AQAQ | 20 (40 μL) | 200 μL |
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FN1 Gene Summary
This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined. [provided by RefSeq, Jan 2016]
Gene Name: Fibronectin 1
Chromosome: CHR2: 216225178 -216300791
Locus: 2q35
SH3GL1 Gene Summary
This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Gene Name: SH3 Domain Containing GRB2 Like 1, Endophilin A2
Chromosome: CHR19: 4360363 -4400565
Locus: 19p13.3
Gene Diseases
The SH3GL1 FN1 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Chromophobe |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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