SH3GL1-DPP9 Fusion FISH Probe
The SH3GL1-DPP9 Fusion FISH Probe is used to confirm a fusion of the SH3GL1 and DPP9 genes. The fusion of the SH3GL1 and DPP9 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SH3GL1-DPP9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-RERE | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-REOR | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-REGO | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-REGR | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-REAQ | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-ORRE | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-OROR | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-ORGO | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-ORAQ | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-GORE | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-GOOR | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-GOGO | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-GOGR | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-GOAQ | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-GRRE | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-GROR | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-GRGO | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-GRGR | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-GRAQ | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-AQRE | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-AQOR | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-AQGO | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-AQGR | 20 (40 μL) | 200 μL |
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| SH3GL1-DPP9-20-AQAQ | 20 (40 μL) | 200 μL |
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SH3GL1 Gene Summary
This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Gene Name: SH3 Domain Containing GRB2 Like 1, Endophilin A2
Chromosome: CHR19: 4360363 -4400565
Locus: 19p13.3
DPP9 Gene Summary
This gene encodes a protein that is a member of the S9B family in clan SC of the serine proteases. The protein has been shown to have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Although the activity of this protein is similar to that of dipeptidyl peptidase 4 (DPP4), it does not appear to be membrane bound. In general, dipeptidyl peptidases appear to be involved in the regulation of the activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. Several transcript variants of this gene have been described but not fully characterized. [provided by RefSeq, Jul 2008]
Gene Name: Dipeptidyl Peptidase 9
Chromosome: CHR19: 4675243 -4723855
Locus: 19p13.3
Gene Diseases
The SH3GL1 DPP9 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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