SH3BP4-LANCL1 Fusion FISH Probe
The SH3BP4-LANCL1 Fusion FISH Probe is used to confirm a fusion of the SH3BP4 and LANCL1 genes. The fusion of the SH3BP4 and LANCL1 genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SH3BP4-LANCL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-RERE | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-REOR | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-REGO | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-REGR | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-REAQ | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-ORRE | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-OROR | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-ORGO | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-GORE | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-GOOR | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-GOGO | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-GOGR | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-GRRE | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-GROR | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-GRGO | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-GRGR | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-AQRE | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-AQOR | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-AQGO | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-AQGR | 20 (40 μL) | 200 μL |
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| SH3BP4-LANCL1-20-AQAQ | 20 (40 μL) | 200 μL |
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LANCL1 Gene Summary
This gene encodes a loosely associated peripheral membrane protein related to the LanC family of bacterial membrane-associated proteins involved in the biosynthesis of antimicrobial peptides. This protein may play a role as a peptide-modifying enzyme component in eukaryotic cells. Previously considered a member of the G-protein-coupled receptor superfamily, this protein is now in the LanC family. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]
Gene Name: LanC Like 1
Chromosome: CHR2: 211295972 -211341499
Locus: 2q34
SH3BP4 Gene Summary
This gene encodes a protein with 3 Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. This protein is involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of a specific protein receptor. [provided by RefSeq, Jul 2008]
Gene Name: SH3 Domain Binding Protein 4
Chromosome: CHR2: 235860627 -235964358
Locus: 2q37.2
Gene Diseases
The SH3BP4 LANCL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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