SGOL2-FBXO8 Fusion FISH Probe
The SGOL2-FBXO8 Fusion FISH Probe is used to confirm a fusion of the SGOL2 and FBXO8 genes. The fusion of the SGOL2 and FBXO8 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SGOL2-FBXO8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-RERE | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-REOR | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-REGO | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-REGR | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-REAQ | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-ORRE | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-OROR | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-ORGO | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-ORAQ | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-GORE | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-GOOR | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-GOGO | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-GOGR | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-GOAQ | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-GRRE | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-GROR | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-GRGO | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-GRGR | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-GRAQ | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-AQRE | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-AQOR | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-AQGO | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-AQGR | 20 (40 μL) | 200 μL |
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| SGOL2-FBXO8-20-AQAQ | 20 (40 μL) | 200 μL |
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FBXO8 Gene Summary
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity. [provided by RefSeq, Jul 2008]
Gene Name: F-box Protein 8
Chromosome: CHR4: 175157809 -175205402
Locus: 4q34.1
Gene Diseases
The SGOL2 FBXO8 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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