SGMS1-GAB2 Fusion FISH Probe
The SGMS1-GAB2 Fusion FISH Probe is used to confirm a fusion of the SGMS1 and GAB2 genes. The fusion of the SGMS1 and GAB2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SGMS1-GAB2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-RERE | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-REOR | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-REGO | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-REGR | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-REAQ | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-ORRE | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-OROR | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-ORGO | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-GORE | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-GOOR | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-GOGO | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-GOGR | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-GRRE | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-GROR | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-GRGO | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-GRGR | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-AQRE | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-AQOR | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-AQGO | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-AQGR | 20 (40 μL) | 200 μL |
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| SGMS1-GAB2-20-AQAQ | 20 (40 μL) | 200 μL |
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GAB2 Gene Summary
This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009]
Gene Name: GRB2 Associated Binding Protein 2
Chromosome: CHR11: 77926335 -78128868
Locus: 11q14.1
SGMS1 Gene Summary
The protein encoded by this gene is predicted to be a five-pass transmembrane protein. This gene may be predominately expressed in brain. [provided by RefSeq, Jul 2008]
Gene Name: Sphingomyelin Synthase 1
Chromosome: CHR10: 52065344 -52383737
Locus: 10q11.23
Gene Diseases
The SGMS1 GAB2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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