SGK3-NCK1 Fusion FISH Probe
The SGK3-NCK1 Fusion FISH Probe is used to confirm a fusion of the SGK3 and NCK1 genes. The fusion of the SGK3 and NCK1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SGK3-NCK1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-RERE | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-REOR | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-REGO | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-REGR | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-REAQ | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-ORRE | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-OROR | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-ORGO | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-GORE | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-GOOR | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-GOGO | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-GOGR | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-GRRE | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-GROR | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-GRGO | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-GRGR | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-AQRE | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-AQOR | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-AQGO | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-AQGR | 20 (40 μL) | 200 μL |
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| SGK3-NCK1-20-AQAQ | 20 (40 μL) | 200 μL |
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NCK1 Gene Summary
The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Jun 2010]
Gene Name: NCK Adaptor Protein 1
Chromosome: CHR3: 136581049 -136667968
Locus: 3q22.3
SGK3 Gene Summary
This gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: Serum/glucocorticoid Regulated Kinase Family Member 3
Chromosome: CHR8: 67624652 -67774257
Locus: 8q13.1
Gene Diseases
The SGK3 NCK1 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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