SGK3-DNAJC5B Fusion FISH Probe
The SGK3-DNAJC5B Fusion FISH Probe is used to confirm a fusion of the SGK3 and DNAJC5B genes. The fusion of the SGK3 and DNAJC5B genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SGK3-DNAJC5B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-RERE | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-REOR | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-REGO | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-REGR | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-REAQ | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-ORRE | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-OROR | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-ORGO | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-ORAQ | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-GORE | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-GOOR | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-GOGO | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-GOGR | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-GOAQ | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-GRRE | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-GROR | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-GRGO | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-GRGR | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-GRAQ | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-AQRE | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-AQOR | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-AQGO | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-AQGR | 20 (40 μL) | 200 μL |
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| SGK3-DNAJC5B-20-AQAQ | 20 (40 μL) | 200 μL |
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SGK3 Gene Summary
This gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: Serum/glucocorticoid Regulated Kinase Family Member 3
Chromosome: CHR8: 67624652 -67774257
Locus: 8q13.1
DNAJC5B Gene Summary
This gene encodes a member of the DNAJ heat shock protein 40 family of co-chaperone proteins that is characterized by an N-terminal DNAJ domain, a linker region, and a cysteine-rich C-terminal domain. The encoded protein, together with heat shock protein 70, is thought to regulate the proper folding of other proteins. The orthologous mouse protein is membrane-associated and is targeted to the trans-golgi network. [provided by RefSeq, Mar 2017]
Gene Name: DnaJ Heat Shock Protein Family (Hsp40) Member C5 Beta
Chromosome: CHR8: 66933790 -67012755
Locus: 8q13.1
Gene Diseases
The SGK3 DNAJC5B Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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