SGCD-LCP2 Fusion FISH Probe
The SGCD-LCP2 Fusion FISH Probe is used to confirm a fusion of the SGCD and LCP2 genes. The fusion of the SGCD and LCP2 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SGCD-LCP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-RERE | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-REOR | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-REGO | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-REGR | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-REAQ | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-ORRE | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-OROR | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-ORGO | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-GORE | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-GOOR | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-GOGO | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-GOGR | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-GRRE | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-GROR | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-GRGO | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-GRGR | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-AQRE | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-AQOR | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-AQGO | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-AQGR | 20 (40 μL) | 200 μL |
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| SGCD-LCP2-20-AQAQ | 20 (40 μL) | 200 μL |
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LCP2 Gene Summary
This gene encodes an adapter protein that acts as a substrate of the T cell antigen receptor (TCR)-activated protein tyrosine kinase pathway. The encoded protein associates with growth factor receptor bound protein 2, and is thought to play a role TCR-mediated intracellular signal transduction. A similar protein in mouse plays a role in normal T-cell development and activation. Mice lacking this gene show subcutaneous and intraperitoneal fetal hemorrhaging, dysfunctional platelets and impaired viability. [provided by RefSeq, Nov 2016]
Gene Name: Lymphocyte Cytosolic Protein 2
Chromosome: CHR5: 169675087 -169724822
Locus: 5q35.1
SGCD Gene Summary
The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Sarcoglycan Delta
Chromosome: CHR5: 155753766 -156194798
Locus: 5q33.2-q33.3
Gene Diseases
The SGCD LCP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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