SFTPC-ZNFX1 Fusion FISH Probe
The SFTPC-ZNFX1 Fusion FISH Probe is used to confirm a fusion of the SFTPC and ZNFX1 genes. The fusion of the SFTPC and ZNFX1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SFTPC-ZNFX1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-RERE | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-REOR | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-REGO | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-REGR | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-REAQ | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-ORRE | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-OROR | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-ORGO | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-GORE | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-GOOR | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-GOGO | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-GOGR | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-GRRE | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-GROR | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-GRGO | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-GRGR | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-AQRE | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-AQOR | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-AQGO | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-AQGR | 20 (40 μL) | 200 μL |
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| SFTPC-ZNFX1-20-AQAQ | 20 (40 μL) | 200 μL |
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SFTPC Gene Summary
This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.[provided by RefSeq, Feb 2010]
Gene Name: Surfactant Protein C
Chromosome: CHR8: 22019183 -22021991
Locus: 8p21.3
ZNFX1 Gene Summary
The Zinc Finger NFX1-type Containing 1 (ZNFX1) gene is located on chr20 :47862438-47894756 at 20q13.13.
Gene Name: Zinc Finger NFX1-type Containing 1
Chromosome: CHR20: 47862438 -47894756
Locus: 20q13.13
Gene Diseases
The SFTPC ZNFX1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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