SFN-PLAT Fusion FISH Probe
The SFN-PLAT Fusion FISH Probe is used to confirm a fusion of the SFN and PLAT genes. The fusion of the SFN and PLAT genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SFN-PLAT-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-RERE | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-REOR | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-REGO | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-REGR | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-REAQ | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-ORRE | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-OROR | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-ORGO | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-ORAQ | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-GORE | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-GOOR | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-GOGO | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-GOGR | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-GOAQ | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-GRRE | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-GROR | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-GRGO | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-GRGR | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-GRAQ | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-AQRE | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-AQOR | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-AQGO | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-AQGR | 20 (40 μL) | 200 μL |
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| SFN-PLAT-20-AQAQ | 20 (40 μL) | 200 μL |
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SFN Gene Summary
This gene encodes a cell cycle checkpoint protein. The encoded protein binds to translation and initiation factors and functions as a regulator of mitotic translation. In response to DNA damage this protein plays a role in preventing DNA errors during mitosis. [provided by RefSeq, Aug 2017]
Gene Name: Stratifin
Chromosome: CHR1: 27189632 -27190947
Locus: 1p36.11
PLAT Gene Summary
This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
Gene Name: Plasminogen Activator, Tissue Type
Chromosome: CHR8: 42032235 -42065194
Locus: 8p11.21
Gene Diseases
The SFN PLAT Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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