SF3A3-HPCAL4 Fusion FISH Probe
The SF3A3-HPCAL4 Fusion FISH Probe is used to confirm a fusion of the SF3A3 and HPCAL4 genes. The fusion of the SF3A3 and HPCAL4 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SF3A3-HPCAL4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-RERE | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-REOR | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-REGO | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-REGR | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-OROR | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-GORE | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-GROR | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| SF3A3-HPCAL4-20-AQAQ | 20 (40 μL) | 200 μL |
|
SF3A3 Gene Summary
This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Gene Name: Splicing Factor 3a Subunit 3
Chromosome: CHR1: 38422651 -38455761
Locus: 1p34.3
HPCAL4 Gene Summary
The protein encoded by this gene is highly similar to human hippocalcin protein and hippocalcin like-1 protein. It also has similarity to rat neural visinin-like Ca2+-binding protein-type 1 and 2 proteins. This encoded protein may be involved in the calcium-dependent regulation of rhodopsin phosphorylation. The transcript of this gene has multiple polyadenylation sites. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
Gene Name: Hippocalcin Like 4
Chromosome: CHR1: 40144644 -40157089
Locus: 1p34.2
Gene Diseases
The SF3A3 HPCAL4 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|