SETD4-B4GALT6 Fusion FISH Probe
The SETD4-B4GALT6 Fusion FISH Probe is used to confirm a fusion of the SETD4 and B4GALT6 genes. The fusion of the SETD4 and B4GALT6 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SETD4-B4GALT6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-RERE | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-REOR | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-REGO | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-REGR | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-REAQ | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-ORRE | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-OROR | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-ORGO | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-ORAQ | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-GORE | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-GOOR | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-GOGO | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-GOGR | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-GOAQ | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-GRRE | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-GROR | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-GRGO | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-GRGR | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-GRAQ | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-AQRE | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-AQOR | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-AQGO | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-AQGR | 20 (40 μL) | 200 μL |
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| SETD4-B4GALT6-20-AQAQ | 20 (40 μL) | 200 μL |
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B4GALT6 Gene Summary
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene is a lactosylceramide synthase important for glycolipid biosynthesis. [provided by RefSeq, Jul 2008]
Gene Name: Beta-1,4-galactosyltransferase 6
Chromosome: CHR18: 29202208 -29264686
Locus: 18q12.1
SETD4 Gene Summary
The SET Domain Containing 4 (SETD4) gene is located on chr21 :37406840-37432819 at 21q22.12.
Gene Name: SET Domain Containing 4
Chromosome: CHR21: 37406840 -37432819
Locus: 21q22.12
Gene Diseases
The SETD4 B4GALT6 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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