SETD2-CCRL2 Fusion FISH Probe
The SETD2-CCRL2 Fusion FISH Probe is used to confirm a fusion of the SETD2 and CCRL2 genes. The fusion of the SETD2 and CCRL2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SETD2-CCRL2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-RERE | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-REOR | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-REGO | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-REGR | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-REAQ | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-ORRE | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-OROR | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-ORGO | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-GORE | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-GOOR | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-GOGO | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-GOGR | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-GRRE | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-GROR | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-GRGO | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-GRGR | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-AQRE | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-AQOR | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-AQGO | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-AQGR | 20 (40 μL) | 200 μL |
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| SETD2-CCRL2-20-AQAQ | 20 (40 μL) | 200 μL |
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CCRL2 Gene Summary
This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located. [provided by RefSeq, Jul 2008]
Gene Name: C-C Motif Chemokine Receptor Like 2
Chromosome: CHR3: 46448720 -46451014
Locus: 3p21.31
SETD2 Gene Summary
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
Gene Name: SET Domain Containing 2
Chromosome: CHR3: 47057897 -47205467
Locus: 3p21.31
Gene Diseases
The SETD2 CCRL2 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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