SETBP1-NFYC Fusion FISH Probe
The SETBP1-NFYC Fusion FISH Probe is used to confirm a fusion of the SETBP1 and NFYC genes. The fusion of the SETBP1 and NFYC genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SETBP1-NFYC-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-RERE | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-REOR | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-REGO | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-REGR | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-REAQ | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-ORRE | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-OROR | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-ORGO | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-ORAQ | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-GORE | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-GOOR | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-GOGO | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-GOGR | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-GOAQ | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-GRRE | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-GROR | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-GRGO | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-GRGR | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-GRAQ | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-AQRE | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-AQOR | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-AQGO | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-AQGR | 20 (40 μL) | 200 μL |
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| SETBP1-NFYC-20-AQAQ | 20 (40 μL) | 200 μL |
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NFYC Gene Summary
This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Gene Name: Nuclear Transcription Factor Y Subunit Gamma
Chromosome: CHR1: 41157241 -41237275
Locus: 1p34.2
SETBP1 Gene Summary
This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Gene Name: SET Binding Protein 1
Chromosome: CHR18: 42260862 -42648475
Locus: 18q12.3
Gene Diseases
The SETBP1 NFYC Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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