SESN1-ECHDC1 Fusion FISH Probe
The SESN1-ECHDC1 Fusion FISH Probe is used to confirm a fusion of the SESN1 and ECHDC1 genes. The fusion of the SESN1 and ECHDC1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SESN1-ECHDC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-RERE | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-REOR | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-REGO | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-REGR | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-REAQ | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-ORRE | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-OROR | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-ORGO | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-GORE | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-GOOR | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-GOGO | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-GOGR | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-GRRE | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-GROR | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-GRGO | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-GRGR | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-AQRE | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-AQOR | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-AQGO | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-AQGR | 20 (40 μL) | 200 μL |
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| SESN1-ECHDC1-20-AQAQ | 20 (40 μL) | 200 μL |
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SESN1 Gene Summary
This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Gene Name: Sestrin 1
Chromosome: CHR6: 109307639 -109415708
Locus: 6q21
ECHDC1 Gene Summary
The Ethylmalonyl-CoA Decarboxylase 1 (ECHDC1) gene is located on chr6 :127609856-127664754 at 6q22.33.
Gene Name: Ethylmalonyl-CoA Decarboxylase 1
Chromosome: CHR6: 127609856 -127664754
Locus: 6q22.33
Gene Diseases
The SESN1 ECHDC1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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