SERPINA3-RPL23 Fusion FISH Probe
The SERPINA3-RPL23 Fusion FISH Probe is used to confirm a fusion of the SERPINA3 and RPL23 genes. The fusion of the SERPINA3 and RPL23 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SERPINA3-RPL23-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-RERE | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-REOR | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-REGO | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-REGR | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-REAQ | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-ORRE | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-OROR | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-ORGO | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-ORAQ | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-GORE | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-GOOR | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-GOGO | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-GOGR | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-GOAQ | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-GRRE | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-GROR | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-GRGO | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-GRGR | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-GRAQ | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-AQRE | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-AQOR | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-AQGO | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-AQGR | 20 (40 μL) | 200 μL |
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| SERPINA3-RPL23-20-AQAQ | 20 (40 μL) | 200 μL |
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SERPINA3 Gene Summary
The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jul 2008]
Gene Name: Serpin Family A Member 3
Chromosome: CHR14: 95078713 -95090390
Locus: 14q32.13
RPL23 Gene Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L14P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as rpL17 because the encoded protein shares amino acid identity with ribosomal protein L17 from Saccharomyces cerevisiae; however, its official symbol is RPL23. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Gene Name: Ribosomal Protein L23
Chromosome: CHR17: 37006320 -37010053
Locus: 17q12
Gene Diseases
The SERPINA3 RPL23 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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