SERINC5-THBS4 Fusion FISH Probe
The SERINC5-THBS4 Fusion FISH Probe is used to confirm a fusion of the SERINC5 and THBS4 genes. The fusion of the SERINC5 and THBS4 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SERINC5-THBS4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-RERE | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-REOR | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-REGO | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-REGR | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-REAQ | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-ORRE | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-OROR | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-ORGO | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-ORAQ | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-GORE | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-GOOR | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-GOGO | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-GOGR | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-GOAQ | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-GRRE | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-GROR | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-GRGO | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-GRGR | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-GRAQ | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-AQRE | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-AQOR | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-AQGO | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-AQGR | 20 (40 μL) | 200 μL |
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| SERINC5-THBS4-20-AQAQ | 20 (40 μL) | 200 μL |
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THBS4 Gene Summary
The protein encoded by this gene belongs to the thrombospondin protein family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentamer and can bind to heparin and calcium. It is involved in local signaling in the developing and adult nervous system, and it contributes to spinal sensitization and neuropathic pain states. This gene is activated during the stromal response to invasive breast cancer. It may also play a role in inflammatory responses in Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Gene Name: Thrombospondin 4
Chromosome: CHR5: 79331169 -79379107
Locus: 5q14.1
SERINC5 Gene Summary
The Serine Incorporator 5 (SERINC5) gene is located on chr5 :79407049-79551898 at 5q14.1.
Gene Name: Serine Incorporator 5
Chromosome: CHR5: 79407049 -79551898
Locus: 5q14.1
Gene Diseases
The SERINC5 THBS4 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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