SENP5-TCTEX1D2 Fusion FISH Probe
The SENP5-TCTEX1D2 Fusion FISH Probe is used to confirm a fusion of the SENP5 and TCTEX1D2 genes. The fusion of the SENP5 and TCTEX1D2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SENP5-TCTEX1D2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-RERE | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-REOR | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-REGO | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-REGR | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-REAQ | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-ORRE | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-OROR | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-ORGO | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-GORE | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-GOOR | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-GOGO | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-GOGR | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-GRRE | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-GROR | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-GRGO | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-GRGR | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-AQRE | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-AQOR | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-AQGO | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-AQGR | 20 (40 μL) | 200 μL |
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| SENP5-TCTEX1D2-20-AQAQ | 20 (40 μL) | 200 μL |
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SENP5 Gene Summary
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009]
Gene Name: SUMO1/sentrin Specific Peptidase 5
Chromosome: CHR3: 196594726 -196661584
Locus: 3q29
TCTEX1D2 Gene Summary
Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains. This gene encodes a subunit of the human cytoplasmic dynein-2 complex. Mutations in this gene are associated with short-rib thoracic dysplasia 17 with or without polydactyly. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017]
Gene Name: Tctex1 Domain Containing 2
Chromosome: CHR3: 196018089 -196045165
Locus: 3q29
Gene Diseases
The SENP5 TCTEX1D2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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