SENP2-MSH5 Fusion FISH Probe
The SENP2-MSH5 Fusion FISH Probe is used to confirm a fusion of the SENP2 and MSH5 genes. The fusion of the SENP2 and MSH5 genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SENP2-MSH5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-RERE | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-REOR | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-REGO | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-REGR | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-REAQ | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-ORRE | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-OROR | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-ORGO | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-ORAQ | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-GORE | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-GOOR | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-GOGO | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-GOGR | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-GOAQ | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-GRRE | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-GROR | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-GRGO | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-GRGR | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-GRAQ | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-AQRE | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-AQOR | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-AQGO | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-AQGR | 20 (40 μL) | 200 μL |
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| SENP2-MSH5-20-AQAQ | 20 (40 μL) | 200 μL |
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MSH5 Gene Summary
This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms hetero-oligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 6 open reading frame 26 (C6orf26) gene. [provided by RefSeq, Feb 2011]
Gene Name: MutS Homolog 5
Chromosome: CHR6_mcf_hap5: 3087408 -3110152
Locus: 6p21.33
SENP2 Gene Summary
SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.[supplied by OMIM, Apr 2004]
Gene Name: SUMO1/sentrin/SMT3 Specific Peptidase 2
Chromosome: CHR3: 185304030 -185348885
Locus: 3q27.2
Gene Diseases
The SENP2 MSH5 Fusion has been associated with the following diseases:
| Disease Name |
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| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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