SEMA4B-PIAS1 Fusion FISH Probe
The SEMA4B-PIAS1 Fusion FISH Probe is used to confirm a fusion of the SEMA4B and PIAS1 genes. The fusion of the SEMA4B and PIAS1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SEMA4B-PIAS1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-RERE | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-REOR | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-REGO | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-REGR | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-REAQ | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-ORRE | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-OROR | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-ORGO | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-GORE | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-GOOR | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-GOGO | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-GOGR | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-GRRE | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-GROR | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-GRGO | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-GRGR | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-AQRE | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-AQOR | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-AQGO | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-AQGR | 20 (40 μL) | 200 μL |
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| SEMA4B-PIAS1-20-AQAQ | 20 (40 μL) | 200 μL |
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PIAS1 Gene Summary
This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Gene Name: Protein Inhibitor Of Activated STAT 1
Chromosome: CHR15: 68346571 -68480404
Locus: 15q23
SEMA4B Gene Summary
The Semaphorin 4B (SEMA4B) gene is located on chr15 :90728151-90772892 at 15q26.1.
Gene Name: Semaphorin 4B
Chromosome: CHR15: 90728151 -90772892
Locus: 15q26.1
Gene Diseases
The SEMA4B PIAS1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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