SEC24C-CCT5 Fusion FISH Probe
The SEC24C-CCT5 Fusion FISH Probe is used to confirm a fusion of the SEC24C and CCT5 genes. The fusion of the SEC24C and CCT5 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SEC24C-CCT5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-RERE | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-REOR | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-REGO | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-REGR | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-REAQ | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-ORRE | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-OROR | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-ORGO | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-ORAQ | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-GORE | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-GOOR | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-GOGO | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-GOGR | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-GOAQ | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-GRRE | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-GROR | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-GRGO | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-GRGR | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-GRAQ | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-AQRE | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-AQOR | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-AQGO | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-AQGR | 20 (40 μL) | 200 μL |
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| SEC24C-CCT5-20-AQAQ | 20 (40 μL) | 200 μL |
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SEC24C Gene Summary
The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The product of this gene may play a role in shaping the vesicle, as well as in cargo selection and concentration. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Gene Name: SEC24 Homolog C, COPII Coat Complex Component
Chromosome: CHR10: 75504130 -75531933
Locus: 10q22.2
CCT5 Gene Summary
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015]
Gene Name: Chaperonin Containing TCP1 Subunit 5
Chromosome: CHR5: 10250281 -10266501
Locus: 5p15.2
Gene Diseases
The SEC24C CCT5 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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