SEC23B-NAPB Fusion FISH Probe
The SEC23B-NAPB Fusion FISH Probe is used to confirm a fusion of the SEC23B and NAPB genes. The fusion of the SEC23B and NAPB genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SEC23B-NAPB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-RERE | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-REOR | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-REGO | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-REGR | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-REAQ | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-ORRE | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-OROR | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-ORGO | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-ORAQ | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-GORE | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-GOOR | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-GOGO | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-GOGR | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-GOAQ | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-GRRE | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-GROR | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-GRGO | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-GRGR | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-GRAQ | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-AQRE | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-AQOR | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-AQGO | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-AQGR | 20 (40 μL) | 200 μL |
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| SEC23B-NAPB-20-AQAQ | 20 (40 μL) | 200 μL |
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SEC23B Gene Summary
The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010]
Gene Name: Sec23 Homolog B, Coat Complex II Component
Chromosome: CHR20: 18488187 -18542050
Locus: 20p11.23
NAPB Gene Summary
This gene encodes a member of the soluble N-ethyl-maleimide-sensitive fusion attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. This gene encodes the SNAP beta isoform which has been shown to be preferentially expressed in brain tissue. The encoded protein also interacts with the GluR2 α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor subunit C-terminus and may play a role as a chaperone in the molecular processing of the AMPA receptor. [provided by RefSeq, Mar 2017]
Gene Name: NSF Attachment Protein Beta
Chromosome: CHR20: 23355155 -23402156
Locus: 20p11.21
Gene Diseases
The SEC23B NAPB Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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