SEC23B-CNGB3 Fusion FISH Probe
The SEC23B-CNGB3 Fusion FISH Probe is used to confirm a fusion of the SEC23B and CNGB3 genes. The fusion of the SEC23B and CNGB3 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SEC23B-CNGB3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-RERE | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-REOR | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-REGO | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-REGR | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-OROR | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-GORE | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-GROR | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| SEC23B-CNGB3-20-AQAQ | 20 (40 μL) | 200 μL |
|
SEC23B Gene Summary
The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010]
Gene Name: Sec23 Homolog B, Coat Complex II Component
Chromosome: CHR20: 18488187 -18542050
Locus: 20p11.23
CNGB3 Gene Summary
This gene encodes the beta subunit of a cyclic nucleotide-gated ion channel. The encoded beta subunit appears to play a role in modulation of channel function in cone photoreceptors. This heterotetrameric channel is necessary for sensory transduction, and mutations in this gene have been associated with achromatopsia 3, progressive cone dystrophy, and juvenile macular degeneration, also known as Stargardt Disease. [provided by RefSeq, Feb 2010]
Gene Name: Cyclic Nucleotide Gated Channel Beta 3
Chromosome: CHR8: 87586162 -87755903
Locus: 8q21.3
Gene Diseases
The SEC23B CNGB3 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|