SEC22C-MRPS28 Fusion FISH Probe
The SEC22C-MRPS28 Fusion FISH Probe is used to confirm a fusion of the SEC22C and MRPS28 genes. The fusion of the SEC22C and MRPS28 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SEC22C-MRPS28-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-RERE | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-REOR | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-REGO | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-REGR | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-REAQ | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-ORRE | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-OROR | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-ORGO | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-ORAQ | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-GORE | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-GOOR | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-GOGO | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-GOGR | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-GOAQ | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-GRRE | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-GROR | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-GRGO | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-GRGR | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-GRAQ | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-AQRE | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-AQOR | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-AQGO | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-AQGR | 20 (40 μL) | 200 μL |
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| SEC22C-MRPS28-20-AQAQ | 20 (40 μL) | 200 μL |
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SEC22C Gene Summary
This gene encodes a member of the SEC22 family of vesicle trafficking proteins. The encoded protein is localized to the endoplasmic reticulum and may play a role in the early stages of ER-Golgi protein trafficking. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Gene Name: SEC22 Homolog C, Vesicle Trafficking Protein
Chromosome: CHR3: 42589458 -42642572
Locus: 3p22.1
MRPS28 Gene Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that has been called mitochondrial ribosomal protein S35 in the literature. [provided by RefSeq, Jul 2008]
Gene Name: Mitochondrial Ribosomal Protein S28
Chromosome: CHR8: 80831094 -80942506
Locus: 8q21.13
Gene Diseases
The SEC22C MRPS28 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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