SEC16A-RXRA Fusion FISH Probe
The SEC16A-RXRA Fusion FISH Probe is used to confirm a fusion of the SEC16A and RXRA genes. The fusion of the SEC16A and RXRA genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SEC16A-RXRA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-RERE | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-REOR | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-REGO | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-REGR | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-REAQ | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-ORRE | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-OROR | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-ORGO | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-ORAQ | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-GORE | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-GOOR | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-GOGO | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-GOGR | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-GOAQ | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-GRRE | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-GROR | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-GRGO | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-GRGR | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-GRAQ | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-AQRE | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-AQOR | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-AQGO | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-AQGR | 20 (40 μL) | 200 μL |
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| SEC16A-RXRA-20-AQAQ | 20 (40 μL) | 200 μL |
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RXRA Gene Summary
Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]
Gene Name: Retinoid X Receptor Alpha
Chromosome: CHR9: 137218315 -137332431
Locus: 9q34.2
SEC16A Gene Summary
This gene encodes a protein that forms part of the Sec16 complex. This protein has a role in protein transport from the endoplasmic reticulum (ER) to the Golgi and mediates COPII vesicle formation at the transitional ER. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Feb 2013]
Gene Name: SEC16 Homolog A, Endoplasmic Reticulum Export Factor
Chromosome: CHR9: 139334547 -139377507
Locus: 9q34.3
Gene Diseases
The SEC16A RXRA Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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