SDK2-TMTC2 Fusion FISH Probe
The SDK2-TMTC2 Fusion FISH Probe is used to confirm a fusion of the SDK2 and TMTC2 genes. The fusion of the SDK2 and TMTC2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SDK2-TMTC2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-RERE | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-REOR | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-REGO | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-REGR | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-REAQ | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-ORRE | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-OROR | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-ORGO | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-GORE | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-GOOR | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-GOGO | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-GOGR | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-GRRE | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-GROR | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-GRGO | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-GRGR | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-AQRE | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-AQOR | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-AQGO | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-AQGR | 20 (40 μL) | 200 μL |
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| SDK2-TMTC2-20-AQAQ | 20 (40 μL) | 200 μL |
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SDK2 Gene Summary
The protein encoded by this gene is a member of the immunoglobulin superfamily. The protein contains two immunoglobulin domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA, heparin and the cell surface. This protein, and a homologous mouse sequence, are very similar to the Drosophila sidekick gene product but the specific function of this superfamily member is not yet known. Evidence for alternative splicing at this gene locus has been observed but the full-length nature of additional variants has not yet been determined. [provided by RefSeq, Jul 2008]
Gene Name: Sidekick Cell Adhesion Molecule 2
Chromosome: CHR17: 71330522 -71640227
Locus: 17q25.1
TMTC2 Gene Summary
The protein encoded by this gene is an integral membrane protein localized to the endoplasmic reticulum (ER). The encoded protein contains many tetratricopeptide repeats, sequences known for being involved in protein-protein interactions. This protein binds both the calcium uptake pump SERCA2B and the carbohydrate-binding chaperone calnexin, and it appears to play a role in calcium homeostasis in the ER. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
Gene Name: Transmembrane And Tetratricopeptide Repeat Containing 2
Chromosome: CHR12: 83080933 -83528067
Locus: 12q21.31
Gene Diseases
The SDK2 TMTC2 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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