SDHAF2-TPH1 Fusion FISH Probe
The SDHAF2-TPH1 Fusion FISH Probe is used to confirm a fusion of the SDHAF2 and TPH1 genes. The fusion of the SDHAF2 and TPH1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SDHAF2-TPH1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-RERE | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-REOR | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-REGO | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-REGR | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-REAQ | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-ORRE | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-OROR | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-ORGO | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-GORE | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-GOOR | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-GOGO | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-GOGR | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-GRRE | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-GROR | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-GRGO | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-GRGR | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-AQRE | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-AQOR | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-AQGO | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-AQGR | 20 (40 μL) | 200 μL |
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| SDHAF2-TPH1-20-AQAQ | 20 (40 μL) | 200 μL |
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TPH1 Gene Summary
This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.[provided by RefSeq, Apr 2009]
Gene Name: Tryptophan Hydroxylase 1
Chromosome: CHR11: 18042083 -18062335
Locus: 11p15.1
SDHAF2 Gene Summary
This gene encodes a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for activity of the complex. Mutations in this gene are associated with paraganglioma.[provided by RefSeq, Jul 2010]
Gene Name: Succinate Dehydrogenase Complex Assembly Factor 2
Chromosome: CHR11: 61197596 -61214239
Locus: 11q12.2
Gene Diseases
The SDHAF2 TPH1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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