SDF2-RPTOR Fusion FISH Probe
The SDF2-RPTOR Fusion FISH Probe is used to confirm a fusion of the SDF2 and RPTOR genes. The fusion of the SDF2 and RPTOR genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SDF2-RPTOR-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-RERE | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-REOR | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-REGO | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-REGR | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-REAQ | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-ORRE | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-OROR | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-ORGO | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-ORAQ | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-GORE | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-GOOR | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-GOGO | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-GOGR | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-GOAQ | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-GRRE | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-GROR | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-GRGO | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-GRGR | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-GRAQ | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-AQRE | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-AQOR | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-AQGO | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-AQGR | 20 (40 μL) | 200 μL |
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| SDF2-RPTOR-20-AQAQ | 20 (40 μL) | 200 μL |
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SDF2 Gene Summary
The protein encoded by this gene is believed to be a secretory protein. It has regions of similarity to hydrophilic segments of yeast mannosyltransferases. Its expression is ubiquitous and the gene appears to be relatively conserved among mammals. Alternate splicing results in both coding and non-coding variants. A pseudogene of this gene is located on chromosome 15. [provided by RefSeq, Dec 2011]
Gene Name: Stromal Cell Derived Factor 2
Chromosome: CHR17: 26975606 -26988933
Locus: 17q11.2
RPTOR Gene Summary
This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Gene Name: Regulatory Associated Protein Of MTOR Complex 1
Chromosome: CHR17: 78518624 -78940173
Locus: 17q25.3
Gene Diseases
The SDF2 RPTOR Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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