SDCCAG8-CEP170 Fusion FISH Probe
The SDCCAG8-CEP170 Fusion FISH Probe is used to confirm a fusion of the SDCCAG8 and CEP170 genes. The fusion of the SDCCAG8 and CEP170 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SDCCAG8-CEP170-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-RERE | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-REOR | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-REGO | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-REGR | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-REAQ | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-ORRE | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-OROR | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-ORGO | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-ORAQ | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-GORE | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-GOOR | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-GOGO | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-GOGR | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-GOAQ | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-GRRE | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-GROR | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-GRGO | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-GRGR | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-GRAQ | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-AQRE | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-AQOR | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-AQGO | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-AQGR | 20 (40 μL) | 200 μL |
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| SDCCAG8-CEP170-20-AQAQ | 20 (40 μL) | 200 μL |
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CEP170 Gene Summary
The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Centrosomal Protein 170
Chromosome: CHR1: 243287729 -243418708
Locus: 1q43
SDCCAG8 Gene Summary
This gene encodes a centrosome associated protein. This protein may be involved in organizing the centrosome during interphase and mitosis. Mutations in this gene are associated with retinal-renal ciliopathy. [provided by RefSeq, Oct 2010]
Gene Name: Serologically Defined Colon Cancer Antigen 8
Chromosome: CHR1: 243419306 -243663393
Locus: 1q43-q44
Gene Diseases
The SDCCAG8 CEP170 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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