SDCBP-BIRC6 Fusion FISH Probe
The SDCBP-BIRC6 Fusion FISH Probe is used to confirm a fusion of the SDCBP and BIRC6 genes. The fusion of the SDCBP and BIRC6 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SDCBP-BIRC6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-RERE | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-REOR | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-REGO | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-REGR | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-REAQ | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-ORRE | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-OROR | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-ORGO | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-ORAQ | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-GORE | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-GOOR | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-GOGO | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-GOGR | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-GOAQ | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-GRRE | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-GROR | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-GRGO | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-GRGR | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-GRAQ | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-AQRE | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-AQOR | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-AQGO | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-AQGR | 20 (40 μL) | 200 μL |
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| SDCBP-BIRC6-20-AQAQ | 20 (40 μL) | 200 μL |
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SDCBP Gene Summary
The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. Related pseudogenes have been identified on multiple chromosomes. [provided by RefSeq, Jan 2017]
Gene Name: Syndecan Binding Protein
Chromosome: CHR8: 59465727 -59495419
Locus: 8q12.1
BIRC6 Gene Summary
This gene encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. This protein inhibits apoptosis by facilitating the degradation of apoptotic proteins by ubiquitination. [provided by RefSeq, Jul 2008]
Gene Name: Baculoviral IAP Repeat Containing 6
Chromosome: CHR2: 32582095 -32843965
Locus: 2p22.3
Gene Diseases
The SDCBP BIRC6 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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