SDC4-YWHAB Fusion FISH Probe
The SDC4-YWHAB Fusion FISH Probe is used to confirm a fusion of the SDC4 and YWHAB genes. The fusion of the SDC4 and YWHAB genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SDC4-YWHAB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-RERE | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-REOR | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-REGO | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-REGR | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-REAQ | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-ORRE | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-OROR | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-ORGO | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-ORAQ | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-GORE | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-GOOR | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-GOGO | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-GOGR | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-GOAQ | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-GRRE | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-GROR | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-GRGO | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-GRGR | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-GRAQ | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-AQRE | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-AQOR | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-AQGO | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-AQGR | 20 (40 μL) | 200 μL |
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| SDC4-YWHAB-20-AQAQ | 20 (40 μL) | 200 μL |
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SDC4 Gene Summary
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family. This gene is found on chromosome 20, while a pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]
Gene Name: Syndecan 4
Chromosome: CHR20: 43953928 -43977064
Locus: 20q13.12
YWHAB Gene Summary
This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase Activation Protein Beta
Chromosome: CHR20: 43514343 -43537161
Locus: 20q13.12
Gene Diseases
The SDC4 YWHAB Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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