SDC4-EIF2AK2 Fusion FISH Probe
The SDC4-EIF2AK2 Fusion FISH Probe is used to confirm a fusion of the SDC4 and EIF2AK2 genes. The fusion of the SDC4 and EIF2AK2 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SDC4-EIF2AK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-RERE | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-REOR | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-REGO | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-REGR | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-REAQ | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-ORRE | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-OROR | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-ORGO | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-GORE | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-GOOR | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-GOGO | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-GOGR | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-GRRE | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-GROR | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-GRGO | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-GRGR | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-AQRE | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-AQOR | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-AQGO | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-AQGR | 20 (40 μL) | 200 μL |
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| SDC4-EIF2AK2-20-AQAQ | 20 (40 μL) | 200 μL |
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EIF2AK2 Gene Summary
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Name: Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2
Chromosome: CHR2: 37333698 -37384190
Locus: 2p22.2
SDC4 Gene Summary
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family. This gene is found on chromosome 20, while a pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]
Gene Name: Syndecan 4
Chromosome: CHR20: 43953928 -43977064
Locus: 20q13.12
Gene Diseases
The SDC4 EIF2AK2 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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